CK2+ OR HIP UPDATE
CK2+ OR HIP FREE

After the determination of inhibitory concentrations (IC 50) for a range of metal salts (ZnSO 4, Al(mal) 3, CoCl 2, CrO 3, NaAsO 2 and CaCl 2) in Neuro-2a mouse neuroblastoma cells, the effect of CK2 on metal toxicity was investigated by three lines of experiments using CK2 inhibitors, metal ion specific fluorophores and siRNA-mediated knockdown of CK2 expression. This study demonstrates for the first time that CK2 is involved in the regulation of metal uptake and toxicity in neuronal cells. The only way to turn them to Imperial government is through new titles being granted, or existing Duke/King titles being revoked and re-granted by the emperor.Protein kinase CK2 is a pleiotropic tetrameric enzyme, regulating numerous biological processes from cell proliferation to stress response. Note that, when first establishing the Imperial Administration law, all vassals will have Feudal government.

Feudal government status also automatically applies to rulers who are subjugated through war.

The emperor has access to a 'Make Title Inheritable' option, which will make an Imperial vassal change to Feudal government instead - their title will be inheritable and will not need the assent of the emperor from that point on, until and unless it is usurped or revoked by the liege.

The emperor may select one of their options or spend 200 Prestige to override them and usurp the title personally. If the emperor refuses, the viceroy has the opportunity to bribe their liege with favors and/or coin, but failing that the emperor's council will then suggest up to three alternatives - which may include the original heir/usurper if they are liked enough or are the only available ruler in range. This means that, whenever their title is usurped or inherited, the emperor (or their King-tier liege, even if he is also a viceroy) receives an event to assent to their assumption of the title.

All feudal vassals of Duke or King tier who also have Imperial government are automatically considered viceroys.

CK2+ OR HIP FREE

This government type allows free revocation ('free' meaning no tyranny opinion malus it still costs Prestige) of all Duke- and King-tier vassal titles, with the al-Mulk variant also getting free transfer of vassals.

Under the Imperial Administration law, the government type will change to Imperial (or al-Mulk for Muslims - all references to Imperial government from this point will apply equally to the al-Mulk variant).

There is no separate law for establishing viceroyalties - it comes into play only once the Imperial Administration law has been implemented.

CK2+ OR HIP UPDATE

Viceroyalty Update (brought over from CK2Plus and implemented by Due to myriad bugs and gameplay-suboptimal restrictions with the Charlemagne DLC's implementation of viceroyalties, how they work has been radically changed compared to vanilla CK2:

Ck2+ or hip